GLP-1 Agonists for Weight Loss: What You Need to Know About These Game-Changing Medications

GLP-1 Agonists for Weight Loss

The world of weight loss has evolved far beyond crash diets and intense workouts. In fact, science now offers powerful tools to help patients achieve sustainable results. One of the most exciting breakthroughs is GLP-1 agonist therapy. Originally, these medications were developed for diabetes; however, they are now FDA-approved and widely used for medical weight loss.

At IBI Clinic, we provide a personalized, medically supervised approach to GLP-1-based treatment. Therefore, it is important to understand how this therapy works, what to expect, and how it can help you reach your weight-loss goals. Below, we explain everything you need to know.

 

 

 

What Are GLP-1 Agonists?

 

GLP-1 (Glucagon-Like Peptide-1) agonists are injectable medications that mimic a hormone naturally produced in the gut. They work by:

  • Reducing appetite
  • Delaying gastric emptying (so you feel full longer)
  • Improving insulin sensitivity
  • Lowering blood sugar levels

 

Popular GLP-1 agonists include:

  • Semaglutide (Wegovy®, Ozempic®)
  • Tirzepatide (Zepbound®, Mounjaro®) – also a dual GLP-1/GIP agonist with enhanced efficacy
  • Liraglutide (Saxenda®)

 

 

 

 

How Effective Are GLP-1 Agonists for Weight Loss?

Clinical trials and real-world data show significant weight loss results:

 

Medication Average Weight Loss FDA-Approved Use
Semaglutide Up to 15% Obesity & Type 2 Diabetes
Tirzepatide Up to 22% Obesity & Diabetes
Liraglutide 5–10% Weight Management

 

 

Many patients also see improvements in:

  • Blood pressure
  • Cholesterol
  • Blood sugar
  • Inflammatory markers

 

 

 

Who Is a Good Candidate?

You may be eligible if you:

 

  • Have a BMI ≥ 30, or
  • BMI ≥ 27 with weight-related conditions (e.g., hypertension, sleep apnea)
  • Struggle with portion control, cravings, or emotional eating
  • Are committed to lifestyle changes alongside medication

 

Note: GLP-1s Agonists for Weight Loss are not for everyone. They are not recommended during pregnancy, in patients with certain endocrine tumors, or those with significant GI disorders.

 

 

 

 

Common Side Effects

GLP-1 medications are generally well tolerated. Some mild side effects may include:

  • Nausea or vomiting
  • Constipation or diarrhea
  • Fatigue or dizziness during dose escalation

 

At IBI Clinic, we titrate doses gradually and provide anti-nausea support to minimize discomfort.

 

 

 

Our Comprehensive GLP-1 Weight Loss Program

 

At IBI Clinic, we partner with you to ensure sustainable results:

  • Evaluation and Labs: We start with a thorough assessment to understand your health and weight-loss goals.
  • Medication Selection: Then, we determine the right GLP-1 prescription tailored specifically for you.
  • Lifestyle Support: In addition, we provide personalized guidance for nutrition, fitness, and behavior.
  • Monitoring and Adjustments: Furthermore, we track progress and adjust your dosage as needed.
  • Medication Options: Finally, you can access compounded, brand-name, or insurance-covered GLP-1 medications.

 

 

 

GLP-1s vs. Other Non-Surgical Options

 

Treatment Invasive? Avg. Weight Loss Duration Appetite Control
GLP-1 Agonists No 15–22% Ongoing ✅ High
Orbera® Balloon No 10–15% 6 months ✅ Moderate
ESG No 15–20% Long-Term ✅ Moderate
Lifestyle + Rx Support No 5–10% Variable ✅ Moderate

 

 

 

 

Are GLP-1 Agonists Right for You?

 

If you’re ready to lose weight, improve your health, and feel in control again, then GLP-1 therapy could be your breakthrough. Moreover, at IBI Clinic, we combine science with support to help you succeed. In addition, our team provides guidance every step of the way to ensure you stay on track.

At IBI Clinic, we offer a personalized, medically supervised approach to GLP-1-based treatment. First, we assess your health and goals. Next, we design a plan tailored to your needs. Then, we monitor your progress closely, making adjustments as needed. Finally, we provide ongoing support to help you maintain your results for the long term.

Picture of Dr. A. Christopher Ibikunle MD FACS
Dr. A. Christopher Ibikunle MD FACS
Dr A. Christopher Ibikunle (MD, FACS) is a distinguished surgeon with a rich academic and clinical background. After completing his residency at the Cleveland Clinic Foundation, he served as an Active Staff and Assistant Professor of Surgery. Currently, he is a Professor of Surgery at Augusta University/University of Georgia Medical Partnership and a Lead Preceptor for several institutions, including Morehouse University and Philadelphia College of Osteopathic Medicine. Dr. Chris is a fellow of the American College of Surgeons and a member of the American Society for Metabolic and Bariatric Surgery, committed to advancing surgery and patient care.
Be part of our community, and let’s share positivity, insights, and healthy living tips!

Related Posts